8syg: Difference between revisions
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New page: '''Unreleased structure''' The entry 8syg is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of tetradecameric hub domain of CaMKII alpha== | |||
<StructureSection load='8syg' size='340' side='right'caption='[[8syg]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8syg]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SYG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.6Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8syg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8syg OCA], [https://pdbe.org/8syg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8syg RCSB], [https://www.ebi.ac.uk/pdbsum/8syg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8syg ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KCC2A_RAT KCC2A_RAT] CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.<ref>PMID:15312654</ref> [https://www.uniprot.org/uniprot/GFP_AEQVI GFP_AEQVI] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin. | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Aequorea victoria]] | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Chien C-T]] | |||
[[Category: Chiu W]] | |||
[[Category: Khan S]] | |||
Latest revision as of 05:52, 19 June 2024
Cryo-EM structure of tetradecameric hub domain of CaMKII alpha
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