Insulin: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
Michal Harel (talk | contribs)
No edit summary
 
(7 intermediate revisions by 2 users not shown)
Line 2: Line 2:
'''Insulin''' is a peptide [[hormone]] that helps to maintain blood sugar within a healthy range by regulating [[Carbohydrate Metabolism|carbohydrate]] and lipid metabolism throughout the body. It is secreted by specialized cells in the pancreas and acts by binding to [[insulin receptor|insulin receptors]] on other cells. Insulin in its mature form contains two peptide chains connected by [[Cystine|disulfide crosslinks]], and occurs either as monomer or as hexamer. Administering insulin in carefully determined doses at the appropriate times is used in managing [[diabetes]], a chronic condition where the body fails to maintain blood sugar levels by itself.  
'''Insulin''' is a peptide [[hormone]] that helps to maintain blood sugar within a healthy range by regulating [[Carbohydrate Metabolism|carbohydrate]] and lipid metabolism throughout the body. It is secreted by specialized cells in the pancreas and acts by binding to [[insulin receptor|insulin receptors]] on other cells. Insulin in its mature form contains two peptide chains connected by [[Cystine|disulfide crosslinks]], and occurs either as monomer or as hexamer. Administering insulin in carefully determined doses at the appropriate times is used in managing [[diabetes]], a chronic condition where the body fails to maintain blood sugar levels by itself.  


*'''Proinsulin''' is the insulin precursor which is converted in the pancreas to insulin and C-peptide<ref>PMID:403392</ref>.
*'''Leginsulin''' is an insulin-like peptide found in legumes <ref>PMID:30442953</ref>.
*'''Insulin lispro''' is recombinant insulin which has more rapid absorption than regular insulin<ref>PMID:9339963</ref>.  See also [[Insulin lispro]].
*'''Insulin glargine''' is  a long-acting insulin <ref>PMID:10730548</ref>.  See also [[Insulin glargine]].
*'''Insulin detemir''' is a long-acting analog used for patients with type 1 or 2 diabetes <ref>PMID:23110609</ref>.
*'''Insulin desB30''' is an insulin with B chain lacking residue 30 (The) <ref>PMID:31039402</ref>.


==Other Proteopedia pages about or relating to insulin==
==Other Proteopedia pages about or relating to insulin==
Line 8: Line 14:
[[Diabetes & Hypoglycemia]]<br>
[[Diabetes & Hypoglycemia]]<br>
[[Insulin (Hebrew)]]<br>
[[Insulin (Hebrew)]]<br>
[[Insulin glargine]]<br>
[[Insulin aspart]]<br>
[[Insulin_mo-or-sl|Insulin and pro-insulin (Hebrew)]]<br>
[[Insulin_mo-or-sl|Insulin and pro-insulin (Hebrew)]]<br>
[[Insulin aspart]]<br>
[[Insulin-Degrading Enzyme]]<br>
[[Insulin-Degrading Enzyme]]<br>
[[Molecular_Playground/Insulin]]<br>
[[Molecular_Playground/Insulin]]<br>