6zfv: Difference between revisions

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<StructureSection load='6zfv' size='340' side='right'caption='[[6zfv]]' scene=''>
<StructureSection load='6zfv' size='340' side='right'caption='[[6zfv]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6zfv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZFV FirstGlance]. <br>
<table><tr><td colspan='2'>Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZFV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zfv OCA], [https://pdbe.org/6zfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zfv RCSB], [https://www.ebi.ac.uk/pdbsum/6zfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zfv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zfv OCA], [https://pdbe.org/6zfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zfv RCSB], [https://www.ebi.ac.uk/pdbsum/6zfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zfv ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/GATA2_HUMAN GATA2_HUMAN] Deafness-lymphedema-leukemia syndrome;Inherited acute myeloid leukemia;Myelodysplastic syndrome;Monocytopenia with susceptibility to infections. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/GATA2_HUMAN GATA2_HUMAN] Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Broadhurst RW]]
[[Category: Broadhurst RW]]

Latest revision as of 06:10, 19 June 2024

Solution NMR structure of human GATA2 N-terminal zinc finger domain

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