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== Function ==

[https://www.uniprot.org/uniprot/~~LMCO1_MYCTT LMCO1_MYCTT~~] Yellow laccase-like multicopper oxidase that is able to oxidize a variety of phenolic compounds including standard laccase substrates such as 2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) and 2,6-dimethoxyphenol (2,6-DMP) (PubMed:30529567). Can be used for the bioconversion of 2',3,4-trihy-droxychalcone to 3',4'-dihydroxy-aurone, a bioactive aurone recently shown to possess inhibitory activity against several isoforms of the histone deacetylase complex (HDAC) (PubMed:30529567).<ref>PMID:30529567</ref>

[https://www.uniprot.org/uniprot/LMCO1_THET4 LMCO1_THET4] Yellow laccase-like multicopper oxidase that is able to oxidize a variety of phenolic compounds including standard laccase substrates such as 2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) and 2,6-dimethoxyphenol (2,6-DMP) (PubMed:30529567, PubMed:37326583). The existence of an ortho-hydroxy group is crucial for oxidation since pyrogallol and catechol, which contain ortho-hydroxy groups, are readily oxidized, which is not the case for resorcinol and hydroquinone, that contain meta- and para-hydroxy groups, respectively (PubMed:37326583). The same is also true for the existence of a methoxy group in an ortho-position, since 2,6-DMP, guaiacol and ferulic and caffeic acids are also rather easily oxidized compared with the corresponding unsubstituted compound (PubMed:37326583). Can be used for the bioconversion of 2',3,4-trihy-droxychalcone to 3',4'-dihydroxy-aurone, a bioactive aurone recently shown to possess inhibitory activity against several isoforms of the histone deacetylase complex (HDAC) (PubMed:30529567).<ref>PMID:30529567</ref> <ref>PMID:37326583</ref>

== Publication Abstract from PubMed ==

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 </table>
 == Function ==
-[https://www.uniprot.org/uniprot/LMCO1_MYCTT LMCO1_MYCTT] Yellow laccase-like multicopper oxidase that is able to oxidize a variety of phenolic compounds including standard laccase substrates such as 2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) and 2,6-dimethoxyphenol (2,6-DMP) (PubMed:30529567). Can be used for the bioconversion of 2',3,4-trihy-droxychalcone to 3',4'-dihydroxy-aurone, a bioactive aurone recently shown to possess inhibitory activity against several isoforms of the histone deacetylase complex (HDAC) (PubMed:30529567).<ref>PMID:30529567</ref>
+[https://www.uniprot.org/uniprot/LMCO1_THET4 LMCO1_THET4] Yellow laccase-like multicopper oxidase that is able to oxidize a variety of phenolic compounds including standard laccase substrates such as 2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) and 2,6-dimethoxyphenol (2,6-DMP) (PubMed:30529567, PubMed:37326583). The existence of an ortho-hydroxy group is crucial for oxidation since pyrogallol and catechol, which contain ortho-hydroxy groups, are readily oxidized, which is not the case for resorcinol and hydroquinone, that contain meta- and para-hydroxy groups, respectively (PubMed:37326583). The same is also true for the existence of a methoxy group in an ortho-position, since 2,6-DMP, guaiacol and ferulic and caffeic acids are also rather easily oxidized compared with the corresponding unsubstituted compound (PubMed:37326583). Can be used for the bioconversion of 2',3,4-trihy-droxychalcone to 3',4'-dihydroxy-aurone, a bioactive aurone recently shown to possess inhibitory activity against several isoforms of the histone deacetylase complex (HDAC) (PubMed:30529567).<ref>PMID:30529567</ref> <ref>PMID:37326583</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==