1lqa: Difference between revisions

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[[Image:1lqa.jpg|left|200px]]


<!--
==TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH==
The line below this paragraph, containing "STRUCTURE_1lqa", creates the "Structure Box" on the page.
<StructureSection load='1lqa' size='340' side='right'caption='[[1lqa]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1lqa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LQA FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.604&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
{{STRUCTURE_1lqa|  PDB=1lqa  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lqa OCA], [https://pdbe.org/1lqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lqa RCSB], [https://www.ebi.ac.uk/pdbsum/1lqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lqa ProSAT]</span></td></tr>
 
</table>
'''TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH'''
== Function ==
 
[https://www.uniprot.org/uniprot/TAS_ECOLI TAS_ECOLI]
 
== Evolutionary Conservation ==
==Overview==
[[Image:Consurf_key_small.gif|200px|right]]
BACKGROUND: The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function. RESULTS: The structure of the ybgI protein is a toroid composed of six polypeptide chains forming a trimer of dimers. Each polypeptide chain binds two metal ions on the inside of the toroid. CONCLUSION: The toroidal structure is comparable to that of some proteins that are involved in DNA metabolism. The di-nuclear metal site could imply that the specific function of this protein is as a hydrolase-oxidase enzyme.
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lq/1lqa_consurf.spt"</scriptWhenChecked>
1LQA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQA OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==Reference==
  </jmolCheckbox>
Crystal structure of Escherichia coli protein ybgI, a toroidal structure with a dinuclear metal site., Ladner JE, Obmolova G, Teplyakov A, Howard AJ, Khil PP, Camerini-Otero RD, Gilliland GL, BMC Struct Biol. 2003 Sep 30;3:7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14519207 14519207]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lqa ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Camerini-Otero, R D.]]
[[Category: Camerini-Otero RD]]
[[Category: Gilliland, G L.]]
[[Category: Gilliland GL]]
[[Category: Howard, A J.]]
[[Category: Howard AJ]]
[[Category: Khil, P P.]]
[[Category: Khil PP]]
[[Category: Obmolova, G.]]
[[Category: Obmolova G]]
[[Category: S2F, Structure 2.Function Project.]]
[[Category: Teplyakov A]]
[[Category: Teplyakov, A.]]
[[Category: S2f]]
[[Category: Structural genomic]]
[[Category: Structure 2 function project]]
[[Category: Tim barrel]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 00:10:22 2008''
Retrieved from "https://proteopedia.org/1lqa"