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'''Unreleased structure'''


The entry 8qka is ON HOLD
==Structure of K. pneumoniae LpxH in complex with JEDI-852==
 
<StructureSection load='8qka' size='340' side='right'caption='[[8qka]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
Authors: Sooriyaarachchi, S., Bergfors, T., Jones, T.A., Mowbray, S.L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8qka]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QKA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QKA FirstGlance]. <br>
Description: Structure of K. pneumoniae LpxH in complex with JEDI-852
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=VTK:2-[methyl(methylsulfonyl)amino]-~{N}-(4-piperidin-1-ylsulfonylphenyl)benzamide'>VTK</scene></td></tr>
[[Category: Bergfors, T]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qka OCA], [https://pdbe.org/8qka PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qka RCSB], [https://www.ebi.ac.uk/pdbsum/8qka PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qka ProSAT]</span></td></tr>
[[Category: Jones, T.A]]
</table>
[[Category: Mowbray, S.L]]
== Function ==
[[Category: Sooriyaarachchi, S]]
[https://www.uniprot.org/uniprot/LPXH_KLEP7 LPXH_KLEP7] Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.[HAMAP-Rule:MF_00575]
__TOC__
</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Bergfors T]]
[[Category: Jones TA]]
[[Category: Mowbray SL]]
[[Category: Sooriyaarachchi S]]
Retrieved from "https://proteopedia.org/8qka"