8wal: Difference between revisions
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==Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS.== | |||
<StructureSection load='8wal' size='340' side='right'caption='[[8wal]], [[Resolution|resolution]] 8.52Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8wal]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WAL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.52Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=G2L:3-O-METHYOXYETHYL-GUANOSINE-5-MONOPHOSPHATE'>G2L</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene>, <scene name='pdbligand=ILX:4,5-DIHYDROXYISOLEUCINE'>ILX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRX:6-HYDROXYTRYPTOPHAN'>TRX</scene>, <scene name='pdbligand=W0F:[[(2~{S},3~{R},4~{S},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3-methoxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+phosphono+hydrogen+phosphate'>W0F</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wal OCA], [https://pdbe.org/8wal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wal RCSB], [https://www.ebi.ac.uk/pdbsum/8wal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wal ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Chen | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/A0A4X1TRS6_PIG A0A4X1TRS6_PIG] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively.[ARBA:ARBA00054640] | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Wang | [[Category: Homo sapiens]] | ||
[[Category: Wang | [[Category: Large Structures]] | ||
[[Category: Sus scrofa]] | |||
[[Category: Chen X]] | |||
[[Category: Li W]] | |||
[[Category: Liu W]] | |||
[[Category: Qu X]] | |||
[[Category: Ren Y]] | |||
[[Category: Wang Q]] | |||
[[Category: Wang X]] | |||
[[Category: Xu Y]] | |||
Latest revision as of 15:44, 13 August 2026
Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS.
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