8uc7: Difference between revisions

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'''Unreleased structure'''


The entry 8uc7 is ON HOLD  until Paper Publication
==HCN1 complex with propofol==
 
<StructureSection load='8uc7' size='340' side='right'caption='[[8uc7]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8uc7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UC7 FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene>, <scene name='pdbligand=PFL:2,6-BIS(1-METHYLETHYL)PHENOL'>PFL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uc7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uc7 OCA], [https://pdbe.org/8uc7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uc7 RCSB], [https://www.ebi.ac.uk/pdbsum/8uc7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uc7 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/HCN1_HUMAN HCN1_HUMAN] Early infantile epileptic encephalopathy. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/HCN1_HUMAN HCN1_HUMAN] Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). May mediate responses to sour stimuli.<ref>PMID:15351778</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Kim ED]]
[[Category: Nimigean CM]]
Retrieved from "https://proteopedia.org/8uc7"