8qxp: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
New page: '''Unreleased structure''' The entry 8qxp is ON HOLD Authors: Seddon, C., Beis, K. Description: Crystal structure of the outer membrane porin OmpW from Klebsiella pneumoniae [[Category...
 
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 8qxp is ON HOLD
==Crystal structure of the outer membrane porin OmpW from Klebsiella pneumoniae==
<StructureSection load='8qxp' size='340' side='right'caption='[[8qxp]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8qxp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QXP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qxp OCA], [https://pdbe.org/8qxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qxp RCSB], [https://www.ebi.ac.uk/pdbsum/8qxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qxp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/W9B759_KLEPN W9B759_KLEPN]
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Conjugation is the process by which plasmids, including those that carry antibiotic-resistance genes, are mobilized from one bacterium (the donor) to another (the recipient). The conjugation efficiency of IncF-like plasmids relies on the formation of mating-pair stabilization via intimate interactions between outer membrane proteins on the donor (a plasmid-encoded TraN isoform) and recipient bacteria. Conjugation of the R100-1 plasmid into Escherichia coli and Klebsiella pneumoniae (KP) recipients relies on pairing between the plasmid-encoded TraNalpha in the donor and OmpW in the recipient. Here, the crystal structure of K. pneumoniae OmpW (OmpW(KP)) is reported at 3.2 A resolution. OmpW(KP) forms an eight-stranded beta-barrel flanked by extracellular loops. The structures of E. coli OmpW (OmpW(EC)) and OmpW(KP) show high conservation despite sequence variability in the extracellular loops.


Authors: Seddon, C., Beis, K.
Structure of the outer membrane porin OmpW from the pervasive pathogen Klebsiella pneumoniae.,Seddon C, Frankel G, Beis K Acta Crystallogr F Struct Biol Commun. 2024 Jan 1;80(Pt 1):22-27. doi: , 10.1107/S2053230X23010579. Epub 2024 Jan 1. PMID:38206593<ref>PMID:38206593</ref>


Description: Crystal structure of the outer membrane porin OmpW from Klebsiella pneumoniae
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
[[Category: Unreleased Structures]]
</div>
[[Category: Seddon, C]]
<div class="pdbe-citations 8qxp" style="background-color:#fffaf0;"></div>
[[Category: Beis, K]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Beis K]]
[[Category: Seddon C]]
Retrieved from "https://proteopedia.org/8qxp"