8wwz: Difference between revisions
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==Crystal structure of Bacillus subtilis glyceraldehyde-3-phosphate dehydrogenase GapB== | |||
<StructureSection load='8wwz' size='340' side='right'caption='[[8wwz]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8wwz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WWZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wwz OCA], [https://pdbe.org/8wwz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wwz RCSB], [https://www.ebi.ac.uk/pdbsum/8wwz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wwz ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/G3P2_BACSU G3P2_BACSU] Involved in the gluconeogenesis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NADP. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NADP to NADPH. The reduced NADPH is then exchanged with the second NADP, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.<ref>PMID:10799476</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bacillus subtilis subsp. subtilis str. 168]] | |||
[[Category: Large Structures]] | |||
[[Category: Dahal P]] | |||
[[Category: Kim DY]] | |||
[[Category: Kwon E]] | |||
[[Category: Pathak D]] | |||