8r04: Difference between revisions
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==Structure of Staphylococcus aureus ClpP Bound to the Covalent Active Site Inhibitor Cystargolide A== | |||
<StructureSection load='8r04' size='340' side='right'caption='[[8r04]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8r04]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R04 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VSZ:Cystargolide+A+(bound)'>VSZ</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r04 OCA], [https://pdbe.org/8r04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r04 RCSB], [https://www.ebi.ac.uk/pdbsum/8r04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r04 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/CLPP_AQUAE CLPP_AQUAE] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Aquifex aeolicus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Broetz-Oesterhelt H]] | ||
[[Category: | [[Category: Dema T]] | ||
[[Category: Malik | [[Category: Groll M]] | ||
[[Category: | [[Category: Grond S]] | ||
[[Category: Stange | [[Category: Illigmann A]] | ||
[[Category: | [[Category: Kaysser L]] | ||
[[Category: | [[Category: Kulik A]] | ||
[[Category: | [[Category: Kuttenlochner W]] | ||
[[Category: Lakemeyer M]] | |||
[[Category: Liebhart E]] | |||
[[Category: Malik I]] | |||
[[Category: Sieber SA]] | |||
[[Category: Stange P]] | |||
[[Category: Staudt N]] | |||
[[Category: Vielberg M-T]] | |||
[[Category: Wolf F]] | |||
Latest revision as of 10:04, 20 December 2023
Structure of Staphylococcus aureus ClpP Bound to the Covalent Active Site Inhibitor Cystargolide A
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