Flurbiprofen: Difference between revisions
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<StructureSection load='' size='340' side='right' caption=' | <StructureSection load='' size='340' side='right' caption='Flurbiprofen' scene='10/1008224/Cv/1'> | ||
Flurbiprofen is a member of the phenylalkanoic acid derivative family of nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily indicated as a pre-operative anti-miotic (in an ophthalmic solution) as well as orally for arthritis or dental pain. Side effects are analogous to those of [[ibuprofen]]. See also [https://en.wikipedia.org/wiki/Flurbiprofen Flurbiprofen]. | Flurbiprofen is a member of the phenylalkanoic acid derivative family of nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily indicated as a pre-operative anti-miotic (in an ophthalmic solution) as well as orally for arthritis or dental pain. Side effects are analogous to those of [[ibuprofen]]. See also [https://en.wikipedia.org/wiki/Flurbiprofen Flurbiprofen]. | ||
NSAIDs such as Flurbiprofen work by inhibiting the [[cyclooxygenase]] (COX) enzymes, which convert <scene name='97/973110/Cv/3'>arachidonic acid</scene> to <scene name='42/429113/Cv/4'>prostaglandin H2</scene> (PGH2). PGH2, in turn, is converted by other enzymes to several other [[prostaglandins]] (which are mediators of pain, inflammation, and fever) and to thromboxane A2 (which stimulates platelet aggregation, leading to the formation of blood clots). | |||
<scene name='10/1008224/Overall/1'>CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A NON-SELECTIVE INHIBITOR, FLURBIPROFEN</scene> ([[3pgh]]). | |||
<scene name='10/1008224/Binding_site/1'>Flurbiprofen binding site</scene>. | |||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Latest revision as of 09:17, 17 January 2024
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