8x0p: Difference between revisions
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New page: '''Unreleased structure''' The entry 8x0p is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Crystal structure of Tyrosine decarboxylase in complex with the cofactor PLP and inhibitor carbidopa== | |||
<StructureSection load='8x0p' size='340' side='right'caption='[[8x0p]], [[Resolution|resolution]] 3.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8x0p]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Papaver_somniferum Papaver somniferum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8X0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8X0P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.35Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=142:CARBIDOPA'>142</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8x0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8x0p OCA], [https://pdbe.org/8x0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8x0p RCSB], [https://www.ebi.ac.uk/pdbsum/8x0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8x0p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TYDC2_PAPSO TYDC2_PAPSO] Marginally higher substrate specificity for L-DOPA over L-tyrosine. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Papaver somniferum]] | |||
[[Category: Wang H]] | |||
[[Category: Yao M]] | |||
[[Category: Yu J]] | |||
Latest revision as of 06:17, 12 February 2025
Crystal structure of Tyrosine decarboxylase in complex with the cofactor PLP and inhibitor carbidopa
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