8wss: Difference between revisions
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==Cryo-EM structure of Melanin-Concentrating Hormone Receptor 1 with MCH== | |||
<StructureSection load='8wss' size='340' side='right'caption='[[8wss]], [[Resolution|resolution]] 3.01Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8wss]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WSS FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.01Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wss OCA], [https://pdbe.org/8wss PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wss RCSB], [https://www.ebi.ac.uk/pdbsum/8wss PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wss ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref> | ||
[[Category: | == References == | ||
[[Category: Hu | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Wu | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Yuan | [[Category: Mus musculus]] | ||
[[Category: Gu Y]] | |||
[[Category: He Q]] | |||
[[Category: Hu W]] | |||
[[Category: Shan H]] | |||
[[Category: Wu C]] | |||
[[Category: Wu K]] | |||
[[Category: Xu HE]] | |||
[[Category: Yuan Q]] | |||
[[Category: Zhang Y]] | |||
[[Category: Zhao L]] | |||
Latest revision as of 05:56, 19 June 2024
Cryo-EM structure of Melanin-Concentrating Hormone Receptor 1 with MCH
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