8rdc: Difference between revisions
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New page: '''Unreleased structure''' The entry 8rdc is ON HOLD Authors: Hakansson, M., Diehl, C., Peterson, K., Zetterberg, F., Nilsson, U. Description: Galectin-1 in complex with thiogalactosid... |
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==Galectin-1 in complex with thiogalactoside derivative== | |||
<StructureSection load='8rdc' size='340' side='right'caption='[[8rdc]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8rdc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RDC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RDC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YNO:5-bromanyl-3-[(2~{R},3~{R},4~{S},5~{R},6~{R})-4-[4-(4-chloranyl-1,3-thiazol-2-yl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3-methoxy-5-oxidanyl-oxan-2-yl]sulfanyl-pyridine-2-carbonitrile'>YNO</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rdc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rdc OCA], [https://pdbe.org/8rdc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rdc RCSB], [https://www.ebi.ac.uk/pdbsum/8rdc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rdc ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> | ||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Diehl C]] | |||
[[Category: Hakansson M]] | |||
[[Category: Nilsson U]] | |||
[[Category: Peterson K]] | |||
[[Category: Zetterberg F]] | |||
Latest revision as of 06:24, 18 December 2024
Galectin-1 in complex with thiogalactoside derivative
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