8v6y: Difference between revisions

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New page: '''Unreleased structure''' The entry 8v6y is ON HOLD Authors: Wang, H., Shears, S.B. Description: Crystal structure of the core catalytic domain of human inositol phosphate multikinase...
 
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'''Unreleased structure'''


The entry 8v6y is ON HOLD
==Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 3==
 
<StructureSection load='8v6y' size='340' side='right'caption='[[8v6y]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
Authors: Wang, H., Shears, S.B.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8v6y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8V6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8V6Y FirstGlance]. <br>
Description: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 3
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YHN:3-(3,5-dimethylphenyl)-2,1-benzoxazole-5-carboxylic+acid'>YHN</scene></td></tr>
[[Category: Shears, S.B]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8v6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8v6y OCA], [https://pdbe.org/8v6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8v6y RCSB], [https://www.ebi.ac.uk/pdbsum/8v6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8v6y ProSAT]</span></td></tr>
[[Category: Wang, H]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/IPMK_HUMAN IPMK_HUMAN] Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4).<ref>PMID:12027805</ref> <ref>PMID:12223481</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Shears SB]]
[[Category: Wang H]]