8v79: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry 8v79 is ON HOLD~~

==Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 15==

~~Authors: Wang, H., Shears, S.B.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[8v79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8V79 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8V79 FirstGlance].

~~Description:~~ Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 15

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YJH:(3P,5M)-3-[3-(1-cyclobutylpiperidin-4-yl)phenyl]-5-(1H-tetrazol-5-yl)-2,1-benzoxazole'>YJH</scene></td></tr>

[[Category: Shears~~, S.B~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8v79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8v79 OCA], [https://pdbe.org/8v79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8v79 RCSB], [https://www.ebi.ac.uk/pdbsum/8v79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8v79 ProSAT]</td></tr>

[[Category: Wang, H]]

</table>

== Function ==

[https://www.uniprot.org/uniprot/IPMK_HUMAN IPMK_HUMAN] Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4).<ref>PMID:12027805</ref> <ref>PMID:12223481</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Shears SB]]

[[Category: Wang H]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8v79 is ON HOLD
+==Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 15==
+<StructureSection load='8v79' size='340' side='right'caption='[[8v79]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-Authors: Wang, H., Shears, S.B.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8v79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8V79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8V79 FirstGlance]. <br>
-Description: Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 15
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YJH:(3P,5M)-3-[3-(1-cyclobutylpiperidin-4-yl)phenyl]-5-(1H-tetrazol-5-yl)-2,1-benzoxazole'>YJH</scene></td></tr>
-[[Category: Shears, S.B]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8v79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8v79 OCA], [https://pdbe.org/8v79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8v79 RCSB], [https://www.ebi.ac.uk/pdbsum/8v79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8v79 ProSAT]</span></td></tr>
-[[Category: Wang, H]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/IPMK_HUMAN IPMK_HUMAN] Inositol phosphate kinase with a broad substrate specificity. Has a preference for inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4).<ref>PMID:12027805</ref> <ref>PMID:12223481</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Shears SB]]
+[[Category: Wang H]]