1q3l: Difference between revisions

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New page: left|200px<br /> <applet load="1q3l" size="450" color="white" frame="true" align="right" spinBox="true" caption="1q3l, resolution 1.64Å" /> '''Chromodomain Of HP1...
 
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[[Image:1q3l.gif|left|200px]]<br />
<applet load="1q3l" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1q3l, resolution 1.64&Aring;" />
'''Chromodomain Of HP1 Complexed With Histone H3 Tail Containing monomethyllysine 9.'''<br />


==About this Structure==
==Chromodomain Of HP1 Complexed With Histone H3 Tail Containing monomethyllysine 9.==
1Q3L is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1Q3L OCA].  
<StructureSection load='1q3l' size='340' side='right'caption='[[1q3l]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1q3l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q3L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q3L FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLZ:N-METHYL-LYSINE'>MLZ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q3l OCA], [https://pdbe.org/1q3l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q3l RCSB], [https://www.ebi.ac.uk/pdbsum/1q3l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q3l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HP1_DROME HP1_DROME] Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q3/1q3l_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q3l ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Protein complex]]
[[Category: Homo sapiens]]
[[Category: Jacobs, S.A.]]
[[Category: Large Structures]]
[[Category: Khorasanizadeh, S.]]
[[Category: Jacobs SA]]
[[Category: chromatin]]
[[Category: Khorasanizadeh S]]
[[Category: chromodomain]]
[[Category: h3]]
[[Category: histone]]
[[Category: hp1]]
[[Category: methyllysine]]
[[Category: monomethyllysine]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 18:50:09 2007''
Retrieved from "https://proteopedia.org/1q3l"