8r1a: Difference between revisions
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==Model of the membrane-bound GBP1 oligomer== | |||
<StructureSection load='8r1a' size='340' side='right'caption='[[8r1a]], [[Resolution|resolution]] 26.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8r1a]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R1A FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 26.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AF3:ALUMINUM+FLUORIDE'>AF3</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r1a OCA], [https://pdbe.org/8r1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r1a RCSB], [https://www.ebi.ac.uk/pdbsum/8r1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r1a ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Herrmann | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/GBP1_HUMAN GBP1_HUMAN] Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.<ref>PMID:22106366</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Chu X]] | |||
[[Category: Daumke O]] | |||
[[Category: Herrmann C]] | |||
[[Category: Kudryashev M]] | |||
[[Category: Kutsch M]] | |||
[[Category: Lauterjung P]] | |||
[[Category: Weismehl M]] | |||
Latest revision as of 19:51, 8 September 2026
Model of the membrane-bound GBP1 oligomer
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