8wg5: Difference between revisions

Latest revision as of 07:45, 3 July 2024

@@ Line 7: / Line 7: @@
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wg5 OCA], [https://pdbe.org/8wg5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wg5 RCSB], [https://www.ebi.ac.uk/pdbsum/8wg5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wg5 ProSAT]</span></td></tr>
 </table>
-== Disease ==
-[https://www.uniprot.org/uniprot/UBP16_HUMAN UBP16_HUMAN] Note=A chromosomal aberration involving USP16 is a cause of Chronic myelomonocytic leukemia. Inversion inv(21) (q21;q22) with RUNX1/AML1.
 == Function ==
-[https://www.uniprot.org/uniprot/UBP16_HUMAN UBP16_HUMAN] Specifically deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-10' of histone H3, and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.<ref>PMID:10077596</ref> <ref>PMID:11753566</ref> <ref>PMID:17914355</ref>
+[https://www.uniprot.org/uniprot/H4_HUMAN H4_HUMAN]
-== References ==
-<references/>
+==See Also==
+*[[3D structures of ubiquitin|3D structures of ubiquitin]]
 __TOC__
 </StructureSection>