8tr5: Difference between revisions
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==Cryo-EM structure of the rat P2X7 receptor in the apo closed state== | |||
<StructureSection load='8tr5' size='340' side='right'caption='[[8tr5]], [[Resolution|resolution]] 2.53Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8tr5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus Rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TR5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.53Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tr5 OCA], [https://pdbe.org/8tr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tr5 RCSB], [https://www.ebi.ac.uk/pdbsum/8tr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tr5 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/P2RX7_RAT P2RX7_RAT] Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus]] | |||
[[Category: Glasfeld A]] | |||
[[Category: Godsey MH]] | |||
[[Category: Krishnamurthy I]] | |||
[[Category: Lisi NE]] | |||
[[Category: Mansoor SE]] | |||
[[Category: McCarthy AE]] | |||
[[Category: Oken AC]] | |||
Latest revision as of 08:18, 14 August 2024
Cryo-EM structure of the rat P2X7 receptor in the apo closed state
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