8xpq: Difference between revisions
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==Structure of the sea urchin spSLC9C1 in state-2 w/o cAMP dimer== | |||
<StructureSection load='8xpq' size='340' side='right'caption='[[8xpq]], [[Resolution|resolution]] 3.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8xpq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Strongylocentrotus_purpuratus Strongylocentrotus purpuratus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XPQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xpq OCA], [https://pdbe.org/8xpq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xpq RCSB], [https://www.ebi.ac.uk/pdbsum/8xpq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xpq ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SL9C1_STRPU SL9C1_STRPU] Electroneutral sodium:proton antiporter that regulates intracellular pH of sperm along with capacitation and fertility. Activated in response to egg-derived chemoattractants, couples membrane voltage to sodium:proton exchange and transduces membrane hyperpolarization to cytoplasmic alkalization to cAMP signaling and ultimately to sperm motility.<ref>PMID:30022052</ref> <ref>PMID:37880360</ref> <ref>PMID:37880361</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Strongylocentrotus purpuratus]] | |||
[[Category: Qu H]] | |||
[[Category: Zheng X]] | |||
Latest revision as of 12:24, 17 July 2024
Structure of the sea urchin spSLC9C1 in state-2 w/o cAMP dimer
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