Potassium Channel: Difference between revisions
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'''Potassium channels''' (KCh) are subdivided into voltage-gated KCh and calcium-dependent KCh. The latter are subdivided into high- (BK, LKCa), intermediate- and small-conductance KCh (human SK1, rat SK2, SKCa). The T1 domain is a highly conserved N-terminal domain which is responsible for driving the tetramerization of the KCh α subunit. The inward rectifier KCh (IRK) passes current more easily in the inward direction. KCh is activated by [[Phosphatidylinositol bisphosphate (PIP2)]]. MthK is a calcium-dependent KCh from ''Methanobacterium thermoautrophicum''. | '''Potassium channels''' (KCh) are subdivided into '''voltage-gated KCh''' and '''calcium-dependent KCh'''. The latter are subdivided into '''high-''' (BK, LKCa), '''intermediate-''' and '''small-conductance KCh''' (human SK1, rat SK2, SKCa). The '''T1 domain''' is a highly conserved N-terminal domain which is responsible for driving the tetramerization of the KCh α subunit. The '''inward rectifier KCh''' (IRK) passes current more easily in the inward direction. KCh is activated by [[Phosphatidylinositol bisphosphate (PIP2)]]. '''MthK''' is a calcium-dependent KCh from ''Methanobacterium thermoautrophicum''. '''TMEM175''' or '''transmembrane protein 175''' is a KCh in lysosomes essdenial for their acidity<ref>PMID:37524211</ref>. | ||
== 3D structures of Potassium Channels== | == 3D structures of Potassium Channels== | ||
