8r62: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 8r62 is ON HOLD until 2025-11-20~~

==Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition==

~~Authors: Malard, F., Campagne, S.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[8r62]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R62 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8R62 FirstGlance].

~~Description:~~ Solution structure of Risdiplam bound to the RNA duplex formed upon 5''-splice site recognition

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=Y59:7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-1~{H}-pyrido[1,2-a]pyrimidin-4-one'>Y59</scene></td></tr>

[[Category: Campagne, S]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8r62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r62 OCA], [https://pdbe.org/8r62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r62 RCSB], [https://www.ebi.ac.uk/pdbsum/8r62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r62 ProSAT]</td></tr>

[[Category: Malard, F]]

</table>

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Campagne S]]

[[Category: Malard F]]

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-'''Unreleased structure'''
-The entry 8r62 is ON HOLD  until 2025-11-20
+==Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition==
+<StructureSection load='8r62' size='340' side='right'caption='[[8r62]]' scene=''>
-Authors: Malard, F., Campagne, S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8r62]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R62 FirstGlance]. <br>
-Description: Solution structure of Risdiplam bound to the RNA duplex formed upon 5''-splice site recognition
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=Y59:7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-1~{H}-pyrido[1,2-a]pyrimidin-4-one'>Y59</scene></td></tr>
-[[Category: Campagne, S]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r62 OCA], [https://pdbe.org/8r62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r62 RCSB], [https://www.ebi.ac.uk/pdbsum/8r62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r62 ProSAT]</span></td></tr>
-[[Category: Malard, F]]
+</table>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Campagne S]]
+[[Category: Malard F]]