8rp1: Difference between revisions
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New page: '''Unreleased structure''' The entry 8rp1 is ON HOLD Authors: Sung, S., Wilmanns, M. Description: Aminodeoxychorismate synthase complex from Escherichia coli, with glutamine added [[Ca... |
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==Aminodeoxychorismate synthase complex from Escherichia coli, with glutamine added== | |||
<StructureSection load='8rp1' size='340' side='right'caption='[[8rp1]], [[Resolution|resolution]] 1.86Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8rp1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RP1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RP1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr> | ||
[[Category: Sung | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rp1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rp1 OCA], [https://pdbe.org/8rp1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rp1 RCSB], [https://www.ebi.ac.uk/pdbsum/8rp1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rp1 ProSAT]</span></td></tr> | ||
[[Category: Wilmanns | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PABA_ECOLI PABA_ECOLI] Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p-aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB.<ref>PMID:4914080</ref> <ref>PMID:7592344</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Franziska JF]] | |||
[[Category: Schlee S]] | |||
[[Category: Sterner R]] | |||
[[Category: Sung S]] | |||
[[Category: Wilmanns M]] | |||
Latest revision as of 06:16, 29 January 2025
Aminodeoxychorismate synthase complex from Escherichia coli, with glutamine added
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