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[[Image:1pup.gif|left|200px]]


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==CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION==
The line below this paragraph, containing "STRUCTURE_1pup", creates the "Structure Box" on the page.
<StructureSection load='1pup' size='340' side='right'caption='[[1pup]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1pup]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PUP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-ADENINE'>APN</scene>, <scene name='pdbligand=CPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-CYTOSINE'>CPN</scene>, <scene name='pdbligand=GPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-GUANINE'>GPN</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=TPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-THYMINE'>TPN</scene></td></tr>
{{STRUCTURE_1pup|  PDB=1pup  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pup OCA], [https://pdbe.org/1pup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pup RCSB], [https://www.ebi.ac.uk/pdbsum/1pup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pup ProSAT]</span></td></tr>
 
</table>
'''CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION'''
<div style="background-color:#fffaf0;">
 
== Publication Abstract from PubMed ==
 
==Overview==
The crystal structure of a PNA duplex reveals both a right- and a left-handed helix in the unit cell. The helices are wide (28A), large pitched (18bp) with the base pairs perpendicular to the helix axis, thereby demonstrating that PNA besides adapting to oligonucleotide partners also has a unique structure by itself.
The crystal structure of a PNA duplex reveals both a right- and a left-handed helix in the unit cell. The helices are wide (28A), large pitched (18bp) with the base pairs perpendicular to the helix axis, thereby demonstrating that PNA besides adapting to oligonucleotide partners also has a unique structure by itself.


==About this Structure==
Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution.,Rasmussen H, Kastrup JS, Nielsen JN, Nielsen JM, Nielsen PE Nat Struct Biol. 1997 Feb;4(2):98-101. PMID:9033585<ref>PMID:9033585</ref>
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PUP OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution., Rasmussen H, Kastrup JS, Nielsen JN, Nielsen JM, Nielsen PE, Nat Struct Biol. 1997 Feb;4(2):98-101. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9033585 9033585]
</div>
[[Category: Kastrup, J S.]]
<div class="pdbe-citations 1pup" style="background-color:#fffaf0;"></div>
[[Category: Rasmussen, H.]]
== References ==
[[Category: Dna analogue]]
<references/>
[[Category: Double helix]]
__TOC__
[[Category: Peptide nucleic acid]]
</StructureSection>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 05:30:21 2008''
[[Category: Large Structures]]
[[Category: Kastrup JS]]
[[Category: Rasmussen H]]
Retrieved from "https://proteopedia.org/1pup"