8y4l: Difference between revisions
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The | ==The ACID domain of aMED25== | ||
<StructureSection load='8y4l' size='340' side='right'caption='[[8y4l]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8y4l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Y4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Y4L FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8y4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8y4l OCA], [https://pdbe.org/8y4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8y4l RCSB], [https://www.ebi.ac.uk/pdbsum/8y4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8y4l ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MED25_ARATH MED25_ARATH] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Positive regulator of shade avoidance and of jasmonate signaling. Acts in repression of PhyB-mediated light signaling and regulates the expression of FLOWERING LOCUS T (FT) and of CONSTANS (CO).<ref>PMID:12815435</ref> <ref>PMID:17560376</ref> <ref>PMID:18790998</ref> <ref>PMID:19671879</ref> <ref>PMID:21536906</ref> <ref>PMID:21985558</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arabidopsis thaliana]] | |||
[[Category: Large Structures]] | |||
[[Category: Xiong Y]] | |||
[[Category: Yang Y]] | |||
[[Category: Zhu J]] | |||