1q23: Difference between revisions

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[[Image:1q23.gif|left|200px]]


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==Crystal structure of Chloramphenicol acetyltransferase I complexed with Fusidic acid at 2.18 A resolution==
The line below this paragraph, containing "STRUCTURE_1q23", creates the "Structure Box" on the page.
<StructureSection load='1q23' size='340' side='right'caption='[[1q23]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1q23]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q23 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q23 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUA:FUSIDIC+ACID'>FUA</scene></td></tr>
{{STRUCTURE_1q23| PDB=1q23 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q23 OCA], [https://pdbe.org/1q23 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q23 RCSB], [https://www.ebi.ac.uk/pdbsum/1q23 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q23 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAT_ECOLX CAT_ECOLX] This enzyme is an effector of chloramphenicol resistance in bacteria.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q2/1q23_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q23 ConSurf].
<div style="clear:both"></div>


'''Crystal structure of Chloramphenicol acetyltransferase I complexed with Fusidic acid at 2.18 A resolution'''
==See Also==
 
*[[Chloramphenicol acetyltransferase 3D structures|Chloramphenicol acetyltransferase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1Q23 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q23 OCA].
[[Category: Chloramphenicol O-acetyltransferase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Kokkinidis, M.]]
[[Category: Kokkinidis M]]
[[Category: Roidis, A.]]
[[Category: Roidis A]]
[[Category: Cat i]]
[[Category: Fusidic acid]]
[[Category: Trimer]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 05:46:22 2008''