8rky: Difference between revisions
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==X-ray structure of the drug binding domain of AlbA in complex with the KMR-14-14 compound of the pyrrolobenzodiazepines class== | |||
<StructureSection load='8rky' size='340' side='right'caption='[[8rky]], [[Resolution|resolution]] 2.17Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8rky]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_oxytoca Klebsiella oxytoca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RKY FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17Å</td></tr> | |||
[[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1H1Q:~{S}-[(2~{S},3~{S})-2,3-bis(oxidanyl)-4-sulfanyl-butyl]+4-[[5-[[4-[4-[[(6~{a}~{S})-2-methoxy-11-oxidanylidene-6~{a},7,8,9-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-3-yl]oxy]butanoylamino]-1-methyl-pyrrol-2-yl]carbonylamino]-1-benzothiophen-2-yl]carbonylamino]-1-methyl-imidazole-2-carbothioate'>A1H1Q</scene>, <scene name='pdbligand=A1H1R:ethyl+4-[[5-[[4-[4-[[(6~{a}~{S})-2-methoxy-11-oxidanylidene-6~{a},7,8,9-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-3-yl]oxy]butanoylamino]-1-methyl-pyrrol-2-yl]carbonylamino]-1-benzothiophen-2-yl]carbonylamino]-1-methyl-imidazole-2-carboxylate'>A1H1R</scene>, <scene name='pdbligand=DTV:(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL'>DTV</scene></td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rky OCA], [https://pdbe.org/8rky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rky RCSB], [https://www.ebi.ac.uk/pdbsum/8rky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rky ProSAT]</span></td></tr> | ||
[[ | </table> | ||
[[Category: | == Function == | ||
[[Category: Di Palma | [https://www.uniprot.org/uniprot/Q8KRS7_KLEOX Q8KRS7_KLEOX] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Klebsiella oxytoca]] | |||
[[Category: Large Structures]] | |||
[[Category: Di Palma M]] | |||
[[Category: Rahman KM]] | |||
[[Category: Steiner RA]] | |||
[[Category: Surani YM]] | |||
Latest revision as of 06:08, 15 January 2025
X-ray structure of the drug binding domain of AlbA in complex with the KMR-14-14 compound of the pyrrolobenzodiazepines class
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