8w0s: Difference between revisions

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'''Unreleased structure'''


The entry 8w0s is ON HOLD
==Human EBP complexed with compound 3a==
 
<StructureSection load='8w0s' size='340' side='right'caption='[[8w0s]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
Authors: Sun, D., Masureel, M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8w0s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8W0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8W0S FirstGlance]. <br>
Description: Human EBP complexed with compound 3a
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AEV:1-methyl-8-[(oxan-4-yl)methyl]-3-[4-(trifluoromethyl)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione'>A1AEV</scene></td></tr>
[[Category: Masureel, M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8w0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8w0s OCA], [https://pdbe.org/8w0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8w0s RCSB], [https://www.ebi.ac.uk/pdbsum/8w0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8w0s ProSAT]</span></td></tr>
[[Category: Sun, D]]
</table>
== Disease ==
[https://www.uniprot.org/uniprot/EBP_HUMAN EBP_HUMAN] MEND syndrome;X-linked dominant chondrodysplasia punctata. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/EBP_HUMAN EBP_HUMAN] Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers.<ref>PMID:12760743</ref> <ref>PMID:8798407</ref> <ref>PMID:9894009</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Masureel M]]
[[Category: Sun D]]