8s4a: Difference between revisions
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New page: '''Unreleased structure''' The entry 8s4a is ON HOLD Authors: Neumann, P., Ficner, R. Description: CdaA-B04 complex Category: Unreleased Structures Category: Ficner, R [[Catego... |
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==CdaA-B04 complex== | |||
<StructureSection load='8s4a' size='340' side='right'caption='[[8s4a]], [[Resolution|resolution]] 2.23Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8s4a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8S4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8S4A FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.23Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AJO:N~2~-(cyanomethyl)-N~2~-methyl-N-(6-methylpyridin-2-yl)glycinamide'>AJO</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
[[Category: Ficner | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8s4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8s4a OCA], [https://pdbe.org/8s4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8s4a RCSB], [https://www.ebi.ac.uk/pdbsum/8s4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8s4a ProSAT]</span></td></tr> | ||
[[Category: Neumann | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DACA_LISMO DACA_LISMO] Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a signaling compound secreted into the host's cytosol where it triggers the cytosolic surveillance pathway (CSP), a host pathway of innate immunity characterized by expression of beta interferon (IFN-beta) and coregulated genes.<ref>PMID:20508090</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Listeria monocytogenes]] | |||
[[Category: Ficner R]] | |||
[[Category: Neumann P]] | |||
