8yix: Difference between revisions
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New page: '''Unreleased structure''' The entry 8yix is ON HOLD Authors: Han, Y., Han, Q., Tang, Q., Lin, X., Ye, M., Wu, M., Zhang, Y., Liu, K. Description: Cryo-EM structure of human proteasome... |
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==Cryo-EM structure of human proteasome assembly intermediate half-proteasome== | |||
<StructureSection load='8yix' size='340' side='right'caption='[[8yix]], [[Resolution|resolution]] 2.91Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8yix]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YIX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.91Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8yix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8yix OCA], [https://pdbe.org/8yix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8yix RCSB], [https://www.ebi.ac.uk/pdbsum/8yix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8yix ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/PSA1_HUMAN PSA1_HUMAN] The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells (By similarity). | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: | [[Category: Han Q]] | ||
[[Category: Han Y]] | |||
[[Category: Liu K]] | |||
[[Category: Tang Q]] | |||
[[Category: Zhang Y]] | |||
Latest revision as of 06:15, 15 January 2025
Cryo-EM structure of human proteasome assembly intermediate half-proteasome
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