9avu: Difference between revisions

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'''Unreleased structure'''


The entry 9avu is ON HOLD
==Bovine fetal muscle nAChR bound to ACh==
 
<StructureSection load='9avu' size='340' side='right'caption='[[9avu]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
Authors: Li, H., Hibbs, R.E.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9avu]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9AVU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9AVU FirstGlance]. <br>
Description: Bovine fetal muscle nAChR bound to ACh
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene></td></tr>
[[Category: Li, H]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9avu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9avu OCA], [https://pdbe.org/9avu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9avu RCSB], [https://www.ebi.ac.uk/pdbsum/9avu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9avu ProSAT]</span></td></tr>
[[Category: Hibbs, R.E]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACHA_BOVIN ACHA_BOVIN] Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.<ref>PMID:2423878</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Hibbs RE]]
[[Category: Li H]]

Latest revision as of 06:08, 31 July 2024

Bovine fetal muscle nAChR bound to ACh

9avu, resolution 2.45Å

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