9eos: Difference between revisions

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New page: '''Unreleased structure''' The entry 9eos is ON HOLD Authors: Freitag-Pohl, S., Pohl, E. Description: Human serum albumin with myristate Category: Unreleased Structures [[Category:...
 
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'''Unreleased structure'''


The entry 9eos is ON HOLD
==Human serum albumin with myristate==
 
<StructureSection load='9eos' size='340' side='right'caption='[[9eos]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
Authors: Freitag-Pohl, S., Pohl, E.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9eos]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EOS FirstGlance]. <br>
Description: Human serum albumin with myristate
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
[[Category: Pohl, E]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9eos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9eos OCA], [https://pdbe.org/9eos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9eos RCSB], [https://www.ebi.ac.uk/pdbsum/9eos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9eos ProSAT]</span></td></tr>
[[Category: Freitag-Pohl, S]]
</table>
== Disease ==
[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
== Function ==
[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Freitag-Pohl S]]
[[Category: Pohl E]]
Retrieved from "https://proteopedia.org/9eos"