9etv: Difference between revisions

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New page: '''Unreleased structure''' The entry 9etv is ON HOLD Authors: Description: Category: Unreleased Structures
 
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'''Unreleased structure'''


The entry 9etv is ON HOLD
==Holo IDO with a bound inhibitor==
 
<StructureSection load='9etv' size='340' side='right'caption='[[9etv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9etv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ETV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ETV FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.402&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1H61:6-methylimidazo[1,5-a]pyridine'>A1H61</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9etv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9etv OCA], [https://pdbe.org/9etv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9etv RCSB], [https://www.ebi.ac.uk/pdbsum/9etv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9etv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/T23O_DROME T23O_DROME] Catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring (By similarity). Required during larval growth to control the level of potentially harmful free tryptophan in the hemolymph. In the adult the same reaction is the first step in the ommochrome biosynthetic pathway.<ref>PMID:2108317</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Mac Sweeney A]]
[[Category: Wicki M]]

Latest revision as of 08:17, 5 March 2025

Holo IDO with a bound inhibitor

9etv, resolution 2.40Å

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