8z0t: Difference between revisions

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New page: '''Unreleased structure''' The entry 8z0t is ON HOLD Authors: Du, S., Deng, M.J., Xiao, J.Y. Description: Structure of the human ige-fc bound to its high affinity receptor fc(epsilon) ...
 
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'''Unreleased structure'''


The entry 8z0t is ON HOLD
==Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)==
 
<StructureSection load='8z0t' size='340' side='right'caption='[[8z0t]], [[Resolution|resolution]] 3.58&Aring;' scene=''>
Authors: Du, S., Deng, M.J., Xiao, J.Y.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8z0t]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z0T FirstGlance]. <br>
Description: Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.58&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
[[Category: Du, S]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z0t OCA], [https://pdbe.org/8z0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z0t RCSB], [https://www.ebi.ac.uk/pdbsum/8z0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z0t ProSAT]</span></td></tr>
[[Category: Deng, M.J]]
</table>
[[Category: Xiao, J.Y]]
== Function ==
[https://www.uniprot.org/uniprot/FCERA_HUMAN FCERA_HUMAN] Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Deng MJ]]
[[Category: Du S]]
[[Category: Xiao JY]]

Latest revision as of 08:47, 14 July 2024

Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)

8z0t, resolution 3.58Å

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