7h65: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry 7h65 is ON HOLD~~

==THE 1.8 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH N-[1-[2-[[2-hydroxy-3-methyl-3-(4-methylphenyl)-4-oxocyclobuten-1-yl]-phenylmethyl]-6-methyl-1H-indol-3-yl]-2-methylpropan-2-yl]acetamide==

~~Authors: Banner, D.W., Benz, J.M., Schlatter, D., Hilpert, H.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[7h65]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7H65 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7H65 FirstGlance].

~~Description:~~ THE 1.8 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH N-[1-[2-[[2-hydroxy-3-methyl-3-(4-methylphenyl)-4-oxocyclobuten-1-yl]-phenylmethyl]-6-methyl-1H-indol-3-yl]-2-methylpropan-2-yl]acetamide

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AO1:~{N}-[2-methyl-1-[6-methyl-2-[(~{R})-[(3~{S})-3-methyl-3-(4-methylphenyl)-2-oxidanyl-4-oxidanylidene-cyclobuten-1-yl]-phenyl-methyl]-1~{H}-indol-3-yl]propan-2-yl]ethanamide'>A1AO1</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Schlatter, D~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7h65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7h65 OCA], [https://pdbe.org/7h65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7h65 RCSB], [https://www.ebi.ac.uk/pdbsum/7h65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7h65 ProSAT]</td></tr>

[[Category: ~~Hilpert, H~~]]

</table>

[[Category: ~~Banner, D.W~~]]

== Function ==

[[Category: ~~Benz, J.M~~]]

[https://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Banner DW]]

[[Category: Benz JM]]

[[Category: Hilpert H]]

[[Category: Schlatter D]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7h65 is ON HOLD
+==THE 1.8 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH N-[1-[2-[[2-hydroxy-3-methyl-3-(4-methylphenyl)-4-oxocyclobuten-1-yl]-phenylmethyl]-6-methyl-1H-indol-3-yl]-2-methylpropan-2-yl]acetamide==
+<StructureSection load='7h65' size='340' side='right'caption='[[7h65]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-Authors: Banner, D.W., Benz, J.M., Schlatter, D., Hilpert, H.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7h65]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7H65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7H65 FirstGlance]. <br>
-Description: THE 1.8 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH N-[1-[2-[[2-hydroxy-3-methyl-3-(4-methylphenyl)-4-oxocyclobuten-1-yl]-phenylmethyl]-6-methyl-1H-indol-3-yl]-2-methylpropan-2-yl]acetamide
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AO1:~{N}-[2-methyl-1-[6-methyl-2-[(~{R})-[(3~{S})-3-methyl-3-(4-methylphenyl)-2-oxidanyl-4-oxidanylidene-cyclobuten-1-yl]-phenyl-methyl]-1~{H}-indol-3-yl]propan-2-yl]ethanamide'>A1AO1</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Schlatter, D]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7h65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7h65 OCA], [https://pdbe.org/7h65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7h65 RCSB], [https://www.ebi.ac.uk/pdbsum/7h65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7h65 ProSAT]</span></td></tr>
-[[Category: Hilpert, H]]
+</table>
-[[Category: Banner, D.W]]
+== Function ==
-[[Category: Benz, J.M]]
+[https://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Banner DW]]
+[[Category: Benz JM]]
+[[Category: Hilpert H]]
+[[Category: Schlatter D]]