7h6a: Difference between revisions
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New page: '''Unreleased structure''' The entry 7h6a is ON HOLD Authors: Banner, D.W., Benz, J.M., Schlatter, D., Hilpert, H. Description: THE 1.68 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX... |
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==THE 1.68 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH 3-[2-(dimethylamino)-2-oxoethyl]-5-fluoro-1-(naphthalen-1-ylmethyl)indole-2-carboxylic acid (2-carboxy indole)== | |||
<StructureSection load='7h6a' size='340' side='right'caption='[[7h6a]], [[Resolution|resolution]] 1.68Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7h6a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7H6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7H6A FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AO8:3-[2-(dimethylamino)-2-oxidanylidene-ethyl]-5-fluoranyl-1-(naphthalen-1-ylmethyl)indole-2-carboxylic+acid'>A1AO8</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7h6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7h6a OCA], [https://pdbe.org/7h6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7h6a RCSB], [https://www.ebi.ac.uk/pdbsum/7h6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7h6a ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Banner DW]] | |||
[[Category: Benz JM]] | |||
[[Category: Hilpert H]] | |||
[[Category: Schlatter D]] | |||
Latest revision as of 08:22, 4 March 2026
THE 1.68 A CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH 3-[2-(dimethylamino)-2-oxoethyl]-5-fluoro-1-(naphthalen-1-ylmethyl)indole-2-carboxylic acid (2-carboxy indole)
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