8z3j: Difference between revisions
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New page: '''Unreleased structure''' The entry 8z3j is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures |
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==Benzbromarone interferes with the interaction between Hsp90 and Aha1 by interacting with both of them== | |||
<StructureSection load='8z3j' size='340' side='right'caption='[[8z3j]], [[Resolution|resolution]] 1.52Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8z3j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z3J FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=R75:[3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-1-benzofuran-3-yl)methanone'>R75</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z3j OCA], [https://pdbe.org/8z3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z3j RCSB], [https://www.ebi.ac.uk/pdbsum/8z3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z3j ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/AHSA1_HUMAN AHSA1_HUMAN] Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Shi L]] | |||
[[Category: Tang J]] | |||
[[Category: Xu Z]] | |||
[[Category: Zhang N]] | |||
[[Category: Zhong Y]] | |||
Latest revision as of 05:15, 23 April 2025
Benzbromarone interferes with the interaction between Hsp90 and Aha1 by interacting with both of them
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