8zgg: Difference between revisions
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New page: '''Unreleased structure''' The entry 8zgg is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Human lysine O-link glycosylation complex, LH3/ColGalT1 with bound UDP-glucose== | |||
<StructureSection load='8zgg' size='340' side='right'caption='[[8zgg]], [[Resolution|resolution]] 3.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8zgg]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZGG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.75Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=660:[[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-[[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]methyl]phosphinic+acid'>660</scene>, <scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zgg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zgg OCA], [https://pdbe.org/8zgg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zgg RCSB], [https://www.ebi.ac.uk/pdbsum/8zgg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zgg ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/PLOD3_HUMAN PLOD3_HUMAN] Connective tissue disorder due to lysyl hydroxylase-3 deficiency. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PLOD3_HUMAN PLOD3_HUMAN] Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.[UniProtKB:P24802] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Cai Y]] | |||
[[Category: Cao M]] | |||
[[Category: Cao Y]] | |||
[[Category: Li S]] | |||
[[Category: Li W]] | |||
[[Category: Liao R]] | |||
[[Category: Ma P]] | |||
[[Category: Peng J]] | |||
[[Category: Qin A]] | |||
[[Category: Shen Y]] | |||
[[Category: Wang Q]] | |||
[[Category: Xia Y]] | |||
[[Category: Yao D]] | |||
Latest revision as of 06:27, 19 March 2025
Human lysine O-link glycosylation complex, LH3/ColGalT1 with bound UDP-glucose
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