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'''Unreleased structure'''


The entry 8zsr is ON HOLD
==Complex I form respirasome open state bound by proguanil (SC-ProgO)==
 
<StructureSection load='8zsr' size='340' side='right'caption='[[8zsr]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
Authors: Teng, F., He, Z.X., Hu, Y.Q., Xu, C.Y., Guo, R.Y., Zhou, L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8zsr]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZSR FirstGlance]. <br>
Description: Complex I from respirasome open state inhibited by proguanil
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene>, <scene name='pdbligand=3PE:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>3PE</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CDL:CARDIOLIPIN'>CDL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene>, <scene name='pdbligand=PEE:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>PEE</scene>, <scene name='pdbligand=PLX:(9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL'>PLX</scene>, <scene name='pdbligand=XEW:N-(4-chlorophenyl)-N-(propan-2-yl)triimidodicarbonic+diamide'>XEW</scene>, <scene name='pdbligand=ZMP:S-[2-({N-[(2S)-2-HYDROXY-3,3-DIMETHYL-4-(PHOSPHONOOXY)BUTANOYL]-BETA-ALANYL}AMINO)ETHYL]+TETRADECANETHIOATE'>ZMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Guo, R.Y]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zsr OCA], [https://pdbe.org/8zsr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zsr RCSB], [https://www.ebi.ac.uk/pdbsum/8zsr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zsr ProSAT]</span></td></tr>
[[Category: Zhou, L]]
</table>
[[Category: Teng, F]]
== Function ==
[[Category: Xu, C.Y]]
[https://www.uniprot.org/uniprot/NU4LM_PIG NU4LM_PIG] Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
[[Category: He, Z.X]]
__TOC__
[[Category: Hu, Y.Q]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Guo RY]]
[[Category: He ZX]]
[[Category: Hu YQ]]
[[Category: Teng F]]
[[Category: Xu CY]]
[[Category: Zhou L]]
Retrieved from "https://proteopedia.org/8zsr"