9flt: Difference between revisions

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New page: '''Unreleased structure''' The entry 9flt is ON HOLD Authors: Kraemer, A., Paruch, K., Knapp, S., Structural Genomics Consortium (SGC) Description: Crystal structure of human Haspin (G...
 
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'''Unreleased structure'''


The entry 9flt is ON HOLD
==Crystal structure of human Haspin (GSG2) kinase bound to chemical probe MU1920==
 
<StructureSection load='9flt' size='340' side='right'caption='[[9flt]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
Authors: Kraemer, A., Paruch, K., Knapp, S., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9flt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FLT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FLT FirstGlance]. <br>
Description: Crystal structure of human Haspin (GSG2) kinase bound to chemical probe MU1920
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9flt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9flt OCA], [https://pdbe.org/9flt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9flt RCSB], [https://www.ebi.ac.uk/pdbsum/9flt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9flt ProSAT]</span></td></tr>
[[Category: Paruch, K]]
</table>
[[Category: Structural Genomics Consortium (Sgc)]]
== Function ==
[[Category: Kraemer, A]]
[https://www.uniprot.org/uniprot/HASP_HUMAN HASP_HUMAN] Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.<ref>PMID:11228240</ref> <ref>PMID:15681610</ref> <ref>PMID:17084365</ref> <ref>PMID:20705812</ref> <ref>PMID:20929775</ref>
[[Category: Knapp, S]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Knapp S]]
[[Category: Kraemer A]]
[[Category: Paruch K]]
Retrieved from "https://proteopedia.org/9flt"