9c82: Difference between revisions
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New page: '''Unreleased structure''' The entry 9c82 is ON HOLD Authors: Chen, M., Hurley, J.H. Description: Structure of human ULK1C:PI3KC3-C1 supercomplex Category: Unreleased Structures [[... |
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==Structure of human ULK1C:PI3KC3-C1 supercomplex== | |||
<StructureSection load='9c82' size='340' side='right'caption='[[9c82]], [[Resolution|resolution]] 6.84Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9c82]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9C82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9C82 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.84Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9c82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9c82 OCA], [https://pdbe.org/9c82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9c82 RCSB], [https://www.ebi.ac.uk/pdbsum/9c82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9c82 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Chen | == Function == | ||
[https://www.uniprot.org/uniprot/PI3R4_HUMAN PI3R4_HUMAN] Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123).<ref>PMID:20643123</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Chen M]] | |||
[[Category: Hurley JH]] | |||