9clb: Difference between revisions
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New page: '''Unreleased structure''' The entry 9clb is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Crystal structure of Bak bound to the inhibitory aBAK== | |||
<StructureSection load='9clb' size='340' side='right'caption='[[9clb]], [[Resolution|resolution]] 2.86Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9clb]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CLB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9clb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9clb OCA], [https://pdbe.org/9clb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9clb RCSB], [https://www.ebi.ac.uk/pdbsum/9clb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9clb ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BAK_HUMAN BAK_HUMAN] In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.<ref>PMID:8521816</ref> <ref>PMID:17157251</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Arguinchona L]] | |||
[[Category: Baker D]] | |||
[[Category: Bera AK]] | |||
[[Category: Berger SA]] | |||
[[Category: Birkinshaw RW]] | |||
[[Category: Colman PM]] | |||
[[Category: Czabotar PE]] | |||
[[Category: Fairlie WD]] | |||
[[Category: Harris TJ]] | |||
[[Category: Kang A]] | |||
[[Category: Kasapgil S]] | |||
[[Category: Kluck R]] | |||
[[Category: Lee EF]] | |||
[[Category: Miller MS]] | |||
[[Category: Sankaran B]] | |||
[[Category: Smyth S]] | |||
[[Category: Tran S]] | |||
[[Category: Uren R]] | |||