9is8: Difference between revisions
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New page: '''Unreleased structure''' The entry 9is8 is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of AKT1-AtKC1(G315D)== | |||
<StructureSection load='9is8' size='340' side='right'caption='[[9is8]], [[Resolution|resolution]] 2.77Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9is8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IS8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.77Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9is8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9is8 OCA], [https://pdbe.org/9is8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9is8 RCSB], [https://www.ebi.ac.uk/pdbsum/9is8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9is8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/AKT1_ARATH AKT1_ARATH] Highly selective inward-rectifying potassium channel that mediate potassium uptake by plant roots in response to low K(+) conditions, by a calcium-, CBL-, and CIPK-dependent pathway. Positively regulated by phosphorylation by CIPK23. Negatively regulated by a kinase-independent regulatory mechanism involving a competing direct binding of CBL10. Involved in the stomatal regulation by monitoring the turgor pressure in guard cells. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by hyperpolarization. May interact with the cytoskeleton or with regulatory proteins.<ref>PMID:12678562</ref> <ref>PMID:16814720</ref> <ref>PMID:16895985</ref> <ref>PMID:17898163</ref> <ref>PMID:9572739</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arabidopsis thaliana]] | |||
[[Category: Large Structures]] | |||
[[Category: Dongliang L]] | |||
[[Category: Huaizong S]] | |||
[[Category: Yannan Q]] | |||
[[Category: Yuyue T]] | |||
[[Category: Zijie Z]] | |||
Latest revision as of 06:33, 28 May 2025
Cryo-EM structure of AKT1-AtKC1(G315D)
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