9cy7: Difference between revisions
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==Structure of S.pombe Dis3L2 in complex with oligoU RNA substrate== | |||
<StructureSection load='9cy7' size='340' side='right'caption='[[9cy7]], [[Resolution|resolution]] 3.52Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9cy7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_927 Schizosaccharomyces pombe 927] and [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CY7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.52Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9cy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9cy7 OCA], [https://pdbe.org/9cy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9cy7 RCSB], [https://www.ebi.ac.uk/pdbsum/9cy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cy7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DI3L2_SCHPO DI3L2_SCHPO] 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.[HAMAP-Rule:MF_03045]<ref>PMID:23503588</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Schizosaccharomyces pombe 927]] | |||
[[Category: Schizosaccharomyces pombe 972h-]] | |||
[[Category: Garg A]] | |||
[[Category: Joshua-Tor L]] | |||
Latest revision as of 05:28, 6 August 2025
Structure of S.pombe Dis3L2 in complex with oligoU RNA substrate
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