9ga4: Difference between revisions
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New page: '''Unreleased structure''' The entry 9ga4 is ON HOLD Authors: Description: Category: Unreleased Structures |
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==MtUvrA2UvrB2 bound to damaged oligonucleotide== | |||
<StructureSection load='9ga4' size='340' side='right'caption='[[9ga4]], [[Resolution|resolution]] 3.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9ga4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GA4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ga4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ga4 OCA], [https://pdbe.org/9ga4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ga4 RCSB], [https://www.ebi.ac.uk/pdbsum/9ga4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ga4 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/UVRA_MYCTU UVRA_MYCTU] The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. Alone it slightly inhibits RecA-mediated DNA strand exchange, in concert with UvrD1 greatly inhibits RecA-mediated DNA strand exchange.<ref>PMID:20455546</ref> <ref>PMID:22467787</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Bolognesi M]] | |||
[[Category: Capelli R]] | |||
[[Category: Chaves-Sanjuan A]] | |||
[[Category: Ferrara G]] | |||
[[Category: Genta M]] | |||
[[Category: Jeruzalmi D]] | |||
[[Category: Miggiano R]] | |||
[[Category: Rizzi M]] | |||
[[Category: Rossi F]] | |||
Latest revision as of 05:28, 23 April 2025
MtUvrA2UvrB2 bound to damaged oligonucleotide
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