9ixx: Difference between revisions
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==Structural basis of the cysteinyl leukotriene receptor type 2 activation by LTD4== | |||
<StructureSection load='9ixx' size='340' side='right'caption='[[9ixx]], [[Resolution|resolution]] 3.15Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9ixx]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IXX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.15Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LTD:(5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-AZANYL-3-(2-HYDROXY-2-OXOETHYLAMINO)-3-OXIDANYLIDENE-PROPYL]SULFANYL-5-OXIDANYL-ICOSA-7,9,11,14-TETRAENOIC+ACID'>LTD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ixx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ixx OCA], [https://pdbe.org/9ixx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ixx RCSB], [https://www.ebi.ac.uk/pdbsum/9ixx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ixx ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Jiang M]] | |||
[[Category: Xu Y]] | |||
[[Category: Yin W]] | |||
Latest revision as of 09:24, 2 April 2025
Structural basis of the cysteinyl leukotriene receptor type 2 activation by LTD4
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