9d03: Difference between revisions
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New page: '''Unreleased structure''' The entry 9d03 is ON HOLD Authors: Delker, S.L., Edwards, T.E., Abendroth, J. Description: Co-crystal structure of circularly permuted human taspase-1 bound ... |
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==Co-crystal structure of circularly permuted human taspase-1 bound to ligand SMDC1014689 1-(ethenesulfonyl)-4-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl}piperazine== | |||
<StructureSection load='9d03' size='340' side='right'caption='[[9d03]], [[Resolution|resolution]] 2.45Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9d03]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9D03 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9D03 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R1M:1-(ethenylsulfonyl)-4-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl}piperazine'>R1M</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9d03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9d03 OCA], [https://pdbe.org/9d03 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9d03 RCSB], [https://www.ebi.ac.uk/pdbsum/9d03 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9d03 ProSAT]</span></td></tr> | ||
[[Category: Abendroth | </table> | ||
[[Category: Edwards | == Function == | ||
[https://www.uniprot.org/uniprot/TASP1_HUMAN TASP1_HUMAN] Protease involved in MLL processing and, consequently, in the correct expression of the early HOXA gene cluster. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Abendroth J]] | |||
[[Category: Delker SL]] | |||
[[Category: Edwards TE]] | |||
Latest revision as of 08:08, 13 August 2025
Co-crystal structure of circularly permuted human taspase-1 bound to ligand SMDC1014689 1-(ethenesulfonyl)-4-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl}piperazine
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