9gen: Difference between revisions
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New page: '''Unreleased structure''' The entry 9gen is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures |
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==Recombinant Myeloperoxidase bound to nucleosome core particle== | |||
<StructureSection load='9gen' size='340' side='right'caption='[[9gen]], [[Resolution|resolution]] 3.76Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9gen]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GEN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.76Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gen OCA], [https://pdbe.org/9gen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gen RCSB], [https://www.ebi.ac.uk/pdbsum/9gen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gen ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Xenopus laevis]] | |||
[[Category: Burn GL]] | |||
[[Category: Prumbaum D]] | |||
[[Category: Raisch T]] | |||
[[Category: Raunser S]] | |||
[[Category: Tacke S]] | |||
[[Category: Thee S]] | |||
[[Category: Winkler M]] | |||
[[Category: Zychlinsky A]] | |||
Latest revision as of 05:34, 6 August 2025
Recombinant Myeloperoxidase bound to nucleosome core particle
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